5-Amino 1MQ 50mg

5-Amino-1MQ is a small-molecule research compound — not a peptide. It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor. The molecule has been studied in animal models of adipose-tissue metabolism, with published preclinical work examining its effects on NAD+ pool dynamics and on the methyl-donor balance NNMT regulates. We stock 5-Amino-1MQ because the longevity-research community studies it alongside NAD+ precursors and peptide compounds; the same independent third-party testing discipline we apply to peptides applies to small-molecule research compounds.

5-Amino-1MQ is the abbreviated name for 5-amino-1-methylquinolinium iodide. It is a small organic molecule with the empirical formula C10H11IN2 for the iodide salt form and a molecular weight of approximately 286.13 g/mol. Unlike peptides, 5-Amino-1MQ is not synthesized by solid-phase peptide synthesis; it is produced by traditional organic synthesis and supplied as a crystalline solid for laboratory reconstitution in a research-appropriate solvent.

5-Amino-1MQ is sold strictly for laboratory and research use. It is not approved by the FDA or any other regulatory body for human or veterinary use, and nothing in this guide constitutes guidance for human administration.

Published research on 5-Amino-1MQ originated with NNMT-inhibitor screens reported in the mid-2010s. The molecule was characterized as a competitive inhibitor of the NNMT active site that uses nicotinamide as substrate. In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine). Researchers studying NAD+ biology or methyl-donor pools should evaluate primary sources directly and note that NNMT inhibition has distinct mechanistic implications compared to direct NAD+ precursor supplementation with molecules like NMN or NAD+ itself.

Because 5-Amino-1MQ is a small molecule rather than a peptide, the analytical approach is the same in principle but uses methodology tuned for small organics rather than for amino-acid chains. Every batch of MHS Longevity 5-Amino-1MQ is submitted to an independent third-party laboratory before release:

5-Amino-1MQ as a crystalline solid is more thermally stable than most lyophilized peptides — many research protocols allow room-temperature storage of the powder when protected from light and moisture. For long-term stability and consistency we still recommend refrigerated storage of the dry compound and protection from prolonged light exposure. Reconstituted solutions are typically held at 2–8°C and used within the documented stability window. Standard handling precautions for small-molecule research compounds apply.