HCG 5,000iu

$90.00

Free US shipping over $150
HPLC-tested at 99%+ purity
US-based fulfillment

Overview

Description

A reproductive-signaling hormone researched for supporting endocrine communication and gonadal signaling pathways. Often selected in studies focused on hormonal rhythm and downstream hormone-production signaling.

HCG is commonly explored as an upstream messenger in reproductive axis research, making it relevant for endocrine signaling models and fertility-pathway investigations.

Scientific Overview

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone that binds luteinizing hormone (LH) receptors. Research investigates its effects on reproductive endocrine signaling, gonadal hormone-production pathways, and hypothalamic-pituitary-gonadal axis dynamics. It is widely used in experimental models of reproductive endocrinology and endocrine restoration research.

Product Details

Compound: HCG (Human Chorionic Gonadotropin)
Vial Size: 5,000 IU
Form: Lyophilized powder

This product is intended strictly for laboratory research purposes only. It is not approved for human or veterinary use by the FDA or any other regulatory agency. Store in a cool, dry environment prior to reconstitution and handle using appropriate laboratory and aseptic techniques.

Frequently asked questions

Yes. Every batch of HCG 5,000iu undergoes independent third-party testing using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). The Certificate of Analysis is published and accessible from the product page.

HCG 5,000iu sold by MHS Longevity is verified to 99%+ purity, with the result documented in each batch's Certificate of Analysis. Anything below that threshold is rejected before release.

The Certificate of Analysis for HCG 5,000iu is available directly from the product page and on our Third-Party Test Results page. Each COA includes the batch identifier, test date, testing method, and verified purity percentage.

HCG 5,000iu ships from our US-based facility with standard or expedited options. Orders over $150 qualify for free standard US shipping. All orders are packaged discreetly with documented handling protocols.

No. HCG 5,000iu is supplied strictly for laboratory research purposes only. It is not approved by the FDA for human or veterinary use, and it is not intended to diagnose, treat, cure, or prevent any disease.

MHS Longevity is a veteran-owned operation focused on pharmaceutical-grade research compounds. We source from vetted manufacturers, batch-test independently with HPLC and Mass Spectrometry, and publish every Certificate of Analysis. Pricing is transparent and the testing process is documented end-to-end.

Not in the usual sense. HCG is a heterodimeric glycoprotein — two protein subunits (α at 92 amino acids, β at 145 amino acids) non-covalently associated, with both subunits carrying multiple glycosylation modifications. Each subunit is technically a peptide chain, but the active molecule is the full glycosylated heterodimer rather than a short synthetic peptide.

Because the relationship between mass and bioactivity depends on the glycoform pattern. Two batches of HCG with the same protein mass can differ substantially in receptor-binding activity if their glycosylation differs. The International Unit (IU) is defined against a WHO biological reference standard and gives a bioactivity-based measure that is independent of glycoform variation. Research protocols dependent on consistent LHCGR activation typically rely on IU dosing rather than mass dosing.

HCG and LH share the same receptor (LHCGR) and the same α-subunit; they differ in their β-subunits and in their plasma kinetics. The HCG β-subunit has a C-terminal extension (the 'CTP' or carboxy-terminal peptide) absent in LH, which carries additional glycosylation sites and substantially extends the molecule's half-life. As a research tool, HCG produces longer-lasting LHCGR activation than equivalent IU of LH.

HCG is sent to an independent third-party laboratory for immunoreactive-content analysis and bioactivity assay before each batch is released. The lab's identifier, test date, and IU rating traceable to the WHO international standard are published on the Certificate of Analysis for that batch.

Research & buying

The evidence behind HCG 5,000iu and the questions to ask any vendor before you order.

Research details — HCG 5,000iu

HCG, human chorionic gonadotropin, is a heterodimeric glycoprotein hormone — not a synthetic peptide. The molecule was originally isolated from the urine of pregnant women in the 1920s and 1930s, when its role in maintaining the corpus luteum was characterized. HCG remains a fundamental research tool in reproductive endocrinology because it binds the luteinizing-hormone receptor (LHCGR) with high affinity, producing the same downstream signaling as endogenous LH. We supply HCG as a research-grade lyophilized preparation distinct from any pharmaceutical formulation. This guide explains what HCG is, the published research context, and how each batch is verified.

What is HCG?

HCG is built from two non-covalently associated subunits: an α-subunit of 92 amino acids (which is shared with luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone) and a β-subunit of 145 amino acids that is unique to HCG and confers its receptor specificity. Both subunits carry N-linked and O-linked glycosylation. The intact dimer has a molecular weight of approximately 36–40 kDa depending on glycosylation pattern. HCG is supplied as a lyophilized white-to-off-white powder; concentration is expressed in International Units (IU) of biological activity rather than milligrams, because the relationship between mass and bioactivity depends on glycoform composition.

Research context

Published research on HCG centers on the LH-receptor (LHCGR) pharmacology — HCG and LH share a receptor but differ in their plasma half-life (HCG is substantially longer) and in the exact downstream-signaling kinetics. HCG is used as a research tool to drive sustained LHCGR activation in studies of corpus-luteum biology, ovulation triggering in reproductive-research models, testicular Leydig-cell function, and gonadotropin signaling more broadly. The molecule is also a standard reference compound in pregnancy-test development and in pharmacological dose-response work that requires a long-acting LH-receptor agonist.

How HCG quality is verified

HCG verification is more involved than synthetic-peptide verification because the molecule is a glycoprotein — its biological activity depends on correct folding of both subunits, correct non-covalent association of the heterodimer, and a glycosylation pattern that supports receptor binding. Every batch of MHS Longevity HCG 5000IU is submitted to an independent third-party laboratory before release:

HPLC and immunoreactive analysis measure the apparent HCG content. Because HCG is a glycoprotein, simple HPLC peak-area purity is supplemented with immunoreactivity-based quantification using anti-HCG antibodies, which gives a more biologically meaningful purity readout.
Bioactivity assay confirms the IU rating on the vial. The International Unit is defined by biological activity in a reference assay (the WHO 5th International Standard, in current use), so the IU rating on each vial corresponds to a documented bioactivity measurement rather than a mass-based calculation.

What an HCG Certificate of Analysis shows

Compound name. Human chorionic gonadotropin, heterodimeric glycoprotein.
Vial IU rating. 5000 IU bioactivity per vial, traceable to a WHO international standard.
Batch identifier. Unique ID linking certificate to vial.
Test date. When the analysis was performed.
Method. Immunoreactivity-based content assay + bioactivity measurement.
Verified content. The measured immunoreactive HCG content meeting specification.
Lab and signatures. The independent lab performing the analysis.

Storage and handling (research lab context)

Lyophilized HCG should be stored at -20°C or below for extended stability; refrigeration at 2–8°C is acceptable for moderate-duration storage. Once reconstituted in bacteriostatic water, the solution is typically held at 2–8°C and used within the documented stability window — glycoproteins are more sensitive than synthetic peptides to extreme pH, agitation, and prolonged room-temperature exposure. Repeated freeze–thaw cycles should be avoided. Standard aseptic technique applies during reconstitution.

Where to buy HCG 5,000iu

The same eight questions apply whether you're buying HCG 5,000iufrom us or anywhere else. Vendors who can't answer any of them are worth a closer look.

Vendor evaluation checklist

1. Is the Certificate of Analysis public and downloadable?
A vendor unwilling to publish HPLC/MS results for the batch you're buying has nothing to verify their purity claim against.
2. Which testing method was used — HPLC, Mass Spectrometry, or both?
HPLC measures purity. Mass Spectrometry confirms the molecule's identity. Reputable batches go through both.
3. What's the verified purity percentage on the published COA?
Industry research standard is 99%+. Below that, you're paying for a compound diluted with synthesis byproducts.
4. Where does the product ship from?
US-based fulfillment generally means shorter handling times, customs-free delivery, and clearer return remedies.
5. Is the price published at a single list rate, or hidden behind tier locks?
Opaque pricing is a yellow flag. Transparent vendors quote the same number to every customer.
6. What's the free-shipping threshold, if any?
Compare the all-in cost (product + shipping + handling) — not just the headline price.
7. How is the product stored prior to shipment?
Lyophilized peptides degrade with temperature swings. Vendors should disclose temperature-controlled storage.
8. Is there a documented damage-claim and return policy?
Discreet shipping carries handling risk. A clear, written policy protects you when something goes wrong.

HCG 5,000iu — vendor comparison

MHS LongevityThis site
Price
$90
Purity
99%+
Testing
HPLC + MS
COA public
US-based
Free shipping
$150+
Last checked
May 13, 2026

Vendor	Price	Listed purity	Testing method	COA public	US-based	Free shipping	Last checked
MHS LongevityThis site	$90	99%+	HPLC + MS			$150+	May 13, 2026

Competitor data sourced from each vendor's public product page on the date shown. Listed purity reflects each vendor's own published claim; Certificate of Analysis availability is verified at the URL above. Data may have changed since last check.