Kisspeptin-10 10mg

$90.00

Free US shipping over $150
HPLC-tested at 99%+ purity
US-based fulfillment

Overview

Description

A reproductive-axis signaling peptide researched for supporting natural hormonal communication tied to libido, rhythm, and fertility pathways. Often selected when the goal is upstream endocrine messaging rather than direct hormone replacement.

Kisspeptin-10 is commonly explored for promoting healthy reproductive signaling patterns, making it a premium option in endocrine-optimization research.

Scientific Overview

Kisspeptin-10 is a peptide fragment derived from the Kiss1 gene product and studied for stimulating gonadotropin-releasing hormone (GnRH) signaling. Research focuses on its influence over LH/FSH dynamics and hypothalamic-pituitary-gonadal axis regulation in experimental models. It remains a key target in fertility and libido-related endocrine research.

Product Details

Compound: Kisspeptin-10
Vial Size: 10mg
Purity: ≥99%
Form: Lyophilized powder

This product is intended strictly for laboratory research purposes only. It is not approved for human or veterinary use by the FDA or any other regulatory agency. Store in a cool, dry environment prior to reconstitution and handle using appropriate laboratory and aseptic techniques.

Frequently asked questions

Yes. Every batch of Kisspeptin-10 10mg undergoes independent third-party testing using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). The Certificate of Analysis is published and accessible from the product page.

Kisspeptin-10 10mg sold by MHS Longevity is verified to 99%+ purity, with the result documented in each batch's Certificate of Analysis. Anything below that threshold is rejected before release.

The Certificate of Analysis for Kisspeptin-10 10mg is available directly from the product page and on our Third-Party Test Results page. Each COA includes the batch identifier, test date, testing method, and verified purity percentage.

Kisspeptin-10 10mg ships from our US-based facility with standard or expedited options. Orders over $150 qualify for free standard US shipping. All orders are packaged discreetly with documented handling protocols.

No. Kisspeptin-10 10mg is supplied strictly for laboratory research purposes only. It is not approved by the FDA for human or veterinary use, and it is not intended to diagnose, treat, cure, or prevent any disease.

MHS Longevity is a veteran-owned operation focused on pharmaceutical-grade research compounds. We source from vetted manufacturers, batch-test independently with HPLC and Mass Spectrometry, and publish every Certificate of Analysis. Pricing is transparent and the testing process is documented end-to-end.

Kisspeptin-10 has a molecular weight of approximately 1302.5 g/mol, with the empirical formula C63H83N17O14. This is documented on each batch's Certificate of Analysis alongside the Mass Spectrometry result confirming the C-terminal amidation.

Kisspeptin-54 is the parent hormone — a 54-amino-acid peptide processed from the KISS1 gene product. Kisspeptin-10 is the C-terminal 10 residues of kisspeptin-54 (positions 45–54). Receptor-binding studies show the 10-residue fragment retains essentially full agonist activity at GPR54 / KISS1R, which is why Kisspeptin-10 has become the standard research-tool form rather than the longer parent peptide.

Kisspeptin-10 is sent to an independent third-party laboratory for HPLC and Mass Spectrometry analysis before each batch is released. The lab's identifier and test date are published on the Certificate of Analysis for that batch, including explicit confirmation that the C-terminal amide is intact.

The C-terminal Phe-NH2 motif is part of the recognized receptor-binding region of kisspeptin-family peptides. A free-acid C-terminus produces a substantially less active molecule in receptor-binding assays. Quality verification therefore needs to confirm the amidation specifically, not just the overall amino-acid composition.

Research & buying

The evidence behind Kisspeptin-10 10mg and the questions to ask any vendor before you order.

Research details — Kisspeptin-10 10mg

Kisspeptin-10 is a synthetic decapeptide reproducing the C-terminal active fragment of the parent hormone kisspeptin-54 (also known as metastin). The molecule was characterized in the early 2000s after the KISS1 gene was first identified as a metastasis-suppressor and later as a critical regulator of the hypothalamic-pituitary-gonadal axis. The 10-residue fragment retains essentially full agonist activity at the kisspeptin receptor while being short enough to synthesize cleanly, which is why it is now the standard form used in reproductive-endocrinology research. This guide covers what Kisspeptin-10 is, the research context, and how each batch is verified.

What is Kisspeptin-10?

Kisspeptin-10 has the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 — ten amino acids with a C-terminal amide rather than a free carboxylic acid. The molecular weight is approximately 1302.5 g/mol with the empirical formula C63H83N17O14. It is supplied as a lyophilized white powder for laboratory reconstitution.

Kisspeptin-10 is sold strictly for laboratory and research use. It is not approved by the FDA or any other regulatory body for human or veterinary use, and nothing in this guide constitutes guidance for human administration.

Research context

Published research on kisspeptin positions it at the apex of the hypothalamic-pituitary-gonadal axis: kisspeptin neurons in the hypothalamus activate GnRH neurons, which in turn drive luteinizing-hormone and follicle-stimulating-hormone release from the pituitary. Loss-of-function mutations in the kisspeptin receptor (GPR54 / KISS1R) cause hypogonadotropic hypogonadism in humans, which established the molecule's pathway-critical role. Exogenous kisspeptin administration has been studied extensively in fertility, puberty, and reproductive-endocrinology research. Researchers should consult primary sources from the de Roux, Seminara, and Plant laboratories that established the pathway in the early 2000s.

How Kisspeptin-10 quality is verified

Every batch of MHS Longevity Kisspeptin-10 is submitted to an independent third-party laboratory before release:

HPLC separates components by chemistry and measures the kisspeptin-10 peak as a percentage of total peak area. Anything below 99% is rejected. Deletion variants from incomplete amino-acid couplings during synthesis elute at distinguishable retention times and are flagged.
Mass Spectrometry confirms the 10-residue mass and — importantly — that the C-terminal amidation is intact. A free-acid C-terminus differs from the amidated form by 1 Da, well within MS resolution. This matters because the C-terminus is critical for receptor binding.

What a Kisspeptin-10 Certificate of Analysis shows

Compound name and structural designation. Kisspeptin-10 / metastin-10, with sequence notation including the C-terminal amide.
Batch identifier. Unique ID linking certificate to vial.
Test date. When the analysis was performed.
Method. HPLC, MS, or both, with column and mobile-phase notes.
Verified purity %. The HPLC result. We require 99%+.
C-terminal modification confirmation. Mass spectrometry confirms the amidated C-terminus (mass difference of -1 Da vs free acid).
Lab and signatures. The independent lab performing the analysis.

Storage and handling (research lab context)

Lyophilized Kisspeptin-10 should be stored at -20°C or below for extended stability. Once reconstituted in bacteriostatic water, the solution is typically held at 2–8°C and used within the documented stability window. Tryptophan-containing peptides like Kisspeptin-10 are sensitive to light exposure and oxidation; the powder should be protected from light and the reconstituted solution kept in low-oxygen conditions where practical. Standard aseptic technique applies during reconstitution.

Vendor evaluation checklist

1. Is the Certificate of Analysis public and downloadable?
A vendor unwilling to publish HPLC/MS results for the batch you're buying has nothing to verify their purity claim against.
2. Which testing method was used — HPLC, Mass Spectrometry, or both?
HPLC measures purity. Mass Spectrometry confirms the molecule's identity. Reputable batches go through both.
3. What's the verified purity percentage on the published COA?
Industry research standard is 99%+. Below that, you're paying for a compound diluted with synthesis byproducts.
4. Where does the product ship from?
US-based fulfillment generally means shorter handling times, customs-free delivery, and clearer return remedies.
5. Is the price published at a single list rate, or hidden behind tier locks?
Opaque pricing is a yellow flag. Transparent vendors quote the same number to every customer.
6. What's the free-shipping threshold, if any?
Compare the all-in cost (product + shipping + handling) — not just the headline price.
7. How is the product stored prior to shipment?
Lyophilized peptides degrade with temperature swings. Vendors should disclose temperature-controlled storage.
8. Is there a documented damage-claim and return policy?
Discreet shipping carries handling risk. A clear, written policy protects you when something goes wrong.

Kisspeptin-10 10mg — vendor comparison

MHS LongevityThis site
Price
$90
Purity
99%+
Testing
HPLC + MS
COA public
US-based
Free shipping
$150+
Last checked
May 13, 2026

Vendor	Price	Listed purity	Testing method	COA public	US-based	Free shipping	Last checked
MHS LongevityThis site	$90	99%+	HPLC + MS			$150+	May 13, 2026

Competitor data sourced from each vendor's public product page on the date shown. Listed purity reflects each vendor's own published claim; Certificate of Analysis availability is verified at the URL above. Data may have changed since last check.