Snap-8 10mg
$60.00
- Free US shipping over $150
- HPLC-tested at 99%+ purity
- US-based fulfillment
Overview
Description
A cosmetic peptide researched for supporting a smoother, more relaxed look in high-movement facial areas. Often selected for appearance-focused routines targeting expression-line visibility.
Snap-8 is commonly explored as a refined, topical-friendly peptide option in aesthetic research— useful for clients who want subtle, natural-looking improvements over time.
Scientific Overview
Snap-8 (Acetyl Octapeptide-3) is studied in cosmetic research for its potential to influence neuromuscular signaling linked to facial micro-contractions. Research interest focuses on topical applications and appearance-based outcomes rather than systemic pathways. It is frequently positioned as an advanced peptide option for expression-line–related research.
Product Details
- Compound: Snap-8 (Acetyl Octapeptide-3)
- Vial Size: 10mg
- Purity: ≥99%
- Form: Lyophilized powder
This product is intended strictly for laboratory research purposes only. It is not approved for human or veterinary use by the FDA or any other regulatory agency. Store in a cool, dry environment prior to reconstitution and handle using appropriate laboratory and aseptic techniques.
Frequently asked questions
Yes. Every batch of Snap-8 10mg undergoes independent third-party testing using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). The Certificate of Analysis is published and accessible from the product page.
Snap-8 10mg sold by MHS Longevity is verified to 99%+ purity, with the result documented in each batch's Certificate of Analysis. Anything below that threshold is rejected before release.
The Certificate of Analysis for Snap-8 10mg is available directly from the product page and on our Third-Party Test Results page. Each COA includes the batch identifier, test date, testing method, and verified purity percentage.
Snap-8 10mg ships from our US-based facility with standard or expedited options. Orders over $150 qualify for free standard US shipping. All orders are packaged discreetly with documented handling protocols.
No. Snap-8 10mg is supplied strictly for laboratory research purposes only. It is not approved by the FDA for human or veterinary use, and it is not intended to diagnose, treat, cure, or prevent any disease.
MHS Longevity is a veteran-owned operation focused on pharmaceutical-grade research compounds. We source from vetted manufacturers, batch-test independently with HPLC and Mass Spectrometry, and publish every Certificate of Analysis. Pricing is transparent and the testing process is documented end-to-end.
SNAP-8 has a molecular weight of approximately 889.97 g/mol, with the empirical formula C36H59N13O14S. This is documented on each batch's Certificate of Analysis alongside the Mass Spectrometry result confirming the N-terminal acetylation.
Both are SNARE-related synthetic peptides. Argireline is the 6-residue Ac-Glu-Glu-Met-Gln-Arg-Arg; SNAP-8 extends that sequence by two residues to Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp. SNAP-8 was developed specifically as an extended version of Argireline and is compared to it in the published cosmetic-peptide literature. The two molecules engage the same proposed mechanism (SNARE-complex interference) but at different lengths and with somewhat different reported activity in cell-culture and topical models.
No, not in any clinically relevant sense. Botulinum toxin is a metalloprotease that proteolytically cleaves SNAP-25 (and related SNARE proteins) — irreversibly, at picomolar to nanomolar concentrations. SNAP-8 is a peptide that competes with full SNAP-25 in complex formation, reversibly, and at concentrations many orders of magnitude higher than botulinum toxin requires. The mechanistic analogy is sometimes drawn loosely in marketing-adjacent writing, but the molecules are pharmacologically incomparable.
SNAP-8 is sent to an independent third-party laboratory for HPLC and Mass Spectrometry analysis before each batch is released. The lab's identifier and test date are published on the Certificate of Analysis for that batch, including confirmation of the N-terminal acetylation and absence of methionine-oxidation impurities.
Research & buying
The evidence behind Snap-8 10mg and the questions to ask any vendor before you order.
Research details — Snap-8 10mg
SNAP-8 (also called Acetyl Glutamyl Octapeptide-3) is a synthetic 8-amino-acid peptide modeled on the N-terminus of SNAP-25, the synaptosomal-associated protein essential for SNARE-complex assembly and neurotransmitter release. The molecule was developed as a longer, modified version of Acetyl Hexapeptide-3 (Argireline), extending that earlier cosmetic peptide with two additional residues. Both molecules are studied for their proposed ability to interfere with SNARE-complex formation in a manner mechanistically reminiscent of (but vastly less potent than) botulinum-toxin proteases. This guide explains what SNAP-8 is, the research context, and how each batch is verified.
What is SNAP-8?
SNAP-8 has the sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp — 8 residues with N-terminal acetylation. The molecular weight is approximately 889.97 g/mol with the empirical formula C36H59N13O14S. The acetylated N-terminus is essential to the proposed mechanism, since the unmodified N-terminus does not mimic the corresponding region of native SNAP-25 effectively. It is supplied as a lyophilized white powder for laboratory reconstitution.
SNAP-8 is sold strictly for laboratory and research use. It is not approved by the FDA or any other regulatory body for human or veterinary use, and nothing in this guide constitutes guidance for human administration.
Research context
Published research on SNAP-8 centers on its proposed competition with native SNAP-25 in SNARE-complex assembly. The SNARE complex — comprising SNAP-25, syntaxin, and synaptobrevin — is the core machinery that drives neurotransmitter-vesicle fusion at the synaptic membrane. By presenting a short peptide that resembles the N-terminus of SNAP-25, SNAP-8 has been studied for its ability to interfere with full SNAP-25 incorporation into productive SNARE complexes. The molecule's research interest extends from neurotransmitter-release studies in cultured neurons to formulation research in topical-cosmetic applications. Reported effects vary substantially in magnitude across the literature; researchers should evaluate primary sources directly.
How SNAP-8 quality is verified
Every batch of MHS Longevity SNAP-8 is submitted to an independent third-party laboratory before release. The N-terminal acetylation and the methionine residue (which is oxidation-sensitive) are both specific verification targets:
- HPLC separates components by chemistry. The acetylated and non-acetylated forms elute at distinguishable retention times. Methionine sulfoxide impurities (oxidized Met) also elute separately. Anything below 99% target is rejected.
- Mass Spectrometry confirms the N-terminal acetylation (+42 Da vs non-acetylated form) and rules out methionine-oxidation species (+16 Da vs unoxidized form). Both readouts are clean given SNAP-8's 8-residue length and distinctive composition.
What a SNAP-8 Certificate of Analysis shows
- Compound name and structural designation. SNAP-8 / Acetyl Glutamyl Octapeptide-3, with full sequence and N-terminal acetylation notation.
- Batch identifier. Unique ID linking certificate to vial.
- Test date. When the analysis was performed.
- Method. HPLC, MS, or both, with column and mobile-phase notes.
- Verified purity %. The HPLC result. We require 99%+.
- Acetylation and Met integrity. MS confirms the N-terminal acetylation (+42 Da) and rules out methionine-oxidation impurities.
- Lab and signatures. The independent lab performing the analysis.
Storage and handling (research lab context)
Lyophilized SNAP-8 should be stored at -20°C or below for extended stability. Once reconstituted in bacteriostatic water, the solution is typically held at 2–8°C and used within the documented stability window. The methionine residue is sensitive to oxidative conditions — SNAP-8 should be stored protected from prolonged exposure to atmospheric oxygen where practical, and reconstituted solutions should not be left at room temperature unnecessarily. Single-use aliquoting helps preserve methionine integrity across a study timeline. Standard aseptic technique applies.
Where to buy Snap-8 10mg
The same eight questions apply whether you're buying Snap-8 10mgfrom us or anywhere else. Vendors who can't answer any of them are worth a closer look.
Vendor evaluation checklist
1. Is the Certificate of Analysis public and downloadable?
A vendor unwilling to publish HPLC/MS results for the batch you're buying has nothing to verify their purity claim against.
2. Which testing method was used — HPLC, Mass Spectrometry, or both?
HPLC measures purity. Mass Spectrometry confirms the molecule's identity. Reputable batches go through both.
3. What's the verified purity percentage on the published COA?
Industry research standard is 99%+. Below that, you're paying for a compound diluted with synthesis byproducts.
4. Where does the product ship from?
US-based fulfillment generally means shorter handling times, customs-free delivery, and clearer return remedies.
5. Is the price published at a single list rate, or hidden behind tier locks?
Opaque pricing is a yellow flag. Transparent vendors quote the same number to every customer.
6. What's the free-shipping threshold, if any?
Compare the all-in cost (product + shipping + handling) — not just the headline price.
7. How is the product stored prior to shipment?
Lyophilized peptides degrade with temperature swings. Vendors should disclose temperature-controlled storage.
8. Is there a documented damage-claim and return policy?
Discreet shipping carries handling risk. A clear, written policy protects you when something goes wrong.
MHS LongevityThis site - Price
- $60
- Purity
- 99%+
- Testing
- HPLC + MS
- COA public
- US-based
- Free shipping
- $150+
- Last checked
- May 13, 2026
| Vendor | Price | Listed purity | Testing method | COA public | US-based | Free shipping | Last checked |
|---|---|---|---|---|---|---|---|
MHS LongevityThis site | $60 | 99%+ | HPLC + MS | $150+ | May 13, 2026 |
Competitor data sourced from each vendor's public product page on the date shown. Listed purity reflects each vendor's own published claim; Certificate of Analysis availability is verified at the URL above. Data may have changed since last check.